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Case study: Pediatrics, Diagnosis

Using FeNO for paediatrics asthma diagnosis

A young girl with a family history of asthma and hay fever presented with classic asthma symptoms. FeNO testing played a key role in confirming the diagnosis and guiding treatment.

Last updated: September 2026

Patient profile

Gender/Age: Female under 10 years old
History: Both parents have asthma and hay fever; the patient has hay fever and eczema

Symptoms

  • Cough
  • Chest tightness
  • Wheeze during sports and in cold weather; symptoms worse at night

Diagnostic approach:

Despite the typical asthma symptoms and family history, there was reluctance to make a formal asthma diagnosis. Spirometry is often recommended for children, but pediatric spirometry was not available at this practice.

Serial Peak Flow: Conducted and showed reversible airway obstruction in response to a short-acting bronchodilator, supporting the likelihood of asthma. Not all children can perform peak flow tests, but this patient was able to provide useful data.

Inhaled Corticosteroid (ICS): The positive FeNO result reassured the parents about the need for anti-inflammatory treatment, and the patient was started on an ICS.

FeNO Test:Elevated at 52 ppb, indicating eosinophilic airway inflammation, consistent with asthma.

Outcome:

  • The FeNO test result helped the parents understand the inflammation present in their child’s airways, making them more comfortable with the diagnosis and treatment.
  • Plans were made to repeat the FeNO test after treatment to confirm that the inflammation had been reduced, ensuring effective asthma control.

Clinical Takeaway:

FeNO testing is a valuable tool for diagnosing asthma in children, especially when spirometry is unavailable or difficult to perform. It provides clear evidence of inflammation that helps reassure both clinicians and parents, guiding the appropriate use of inhaled corticosteroids to manage asthma.

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