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Asthma management is supported by national guidelines that were initially created to emphasise the importance of treating the inflammatory nature of the disease to improve patient outcomes (NHLBI 1991). Today, FeNO (fractional exhaled nitric oxide) is a well-established, validated and specific biomarker for T2 driven airway inflammation in asthma 20 years after the Nobel Prize was awarded in 1998 for understanding the importance of nitric oxide in the cardiovascular system.