Important Safety Information | NIOX VERO® User Manual (PDF)
For Healthcare Professionals Only
DistributorsA safe and easy test to instantly transform your asthma care
FeNO stands for fractional exhaled nitric oxide (NO). NO is a molecule produced by the lungs that can be measured in exhaled breath. The discovery of NO in medicine was a real breakthrough, leading to a Nobel Prize in 1998.
Find out more →Asthma is a chronic disease, traditionally diagnosed with tools that show if the lungs are obstructed. However, asthma is actually an inflammatory condition of the airways.1
Find out more →Understanding the level of inflammation with FeNO can lead to improved asthma care. FeNO levels are elevated in asthma and can provide healthcare professionals with the opportunity to see inside a patient’s lungs at the point-of-care.
Find out more →With half of asthma cases misdiagnosed, lung function testing is not enough to make a decision.2 Asthma diagnosis is 7x more likely with a high FeNO level.3
Hypothetical patient reflecting typical clinical experience
She gets breathless when she runs and occasionally at night. Lucy made an appointment to see her doctor to understand what was going on. The doctor performed routine lung function testing and would have ruled out asthma. However when Lucy performed a FeNO test, the result was 73.ppb, indicating airway inflammation. This suggests that Lucy may have asthma.
Hypothetical patient reflecting typical clinical experience
A high FeNO level indicates a greater risk of exacerbation. Using FeNO testing as your asthma risk estimator can help reduce exacerbations by up to 50%.4
Hypothetical patient reflecting typical clinical experience
He has had asthma since the age of 3 and is prescribed an inhaled corticosteroid. Victor still experiences exacerbations and recently visited his doctor. The doctor wanted to check whether Victor was using his inhaler properly and offered him a FeNO test. Victor had a FeNO level of 163.ppb, showing he is non-adherent to his medication and at risk of severe exacerbations. Seeing this number showed Victor how bad the situation actually was. As part of his asthma management plan, Victor tested his FeNO regularly with the aim of reducing his FeNO to a normal level. Seeing his FeNO level reduce at every appointment motivated Victor to keep taking his medication. Victor’s FeNO is now 24.ppb, his inflammation is under control and he has not had an asthma attack in the last year.
Hypothetical patient reflecting typical clinical experience
FeNO testing is the most convenient way to assess airway inflammation at the point-of-care.
One test, one number. Airway inflammation in a single FeNO value.
Performing a FeNO test takes less than two minutes - quicker than making a cup of coffee.
Taking a FeNO test is as simple as inhaling and exhaling: no blood, sweat or tears required.
Your patient performs the test by inhaling and exhaling into the NIOX VERO® breathing handle. After approximately one minute you are presented with a FeNO level. Check this value with internationally recognised cut-off points to decide your next treatment steps.5
Interpreting FeNO → FeNO Guidelines →Breathe
Interpret
Manage
Follow-up
Learn more about the device of choice for FeNO testing.7
Studies have shown that FeNO testing is a cost-effective way to improve patient outcomes. Adding FeNO to the treatment algorithm can considerably reduce costs and improve quality of life when used in combination with current treatment guidelines.
Thousands of healthcare professionals around the world are enjoying the economic and clinical benefits of FeNO testing with NIOX VERO®.
Be more confident with asthma diagnosis
Speed up treatment decisions
Avoid unscheduled visits
Optimise ICS therapy and adherence
Reduce potentially severe exacerbations
Join the thousands of healthcare professionals who have already performed over 45 million FeNO tests with NIOX®, and improve patient outcomes.
1. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. 2021 update. 2. Kavanagh J et al. Over- and under-diagnosis in asthma. Breathe (Sheff). 2019;15(1):e20-e27. 3. Wang Z et al. Agency for Healthcare Research and Quality (AHRQ). The clinical utility of fractional exhaled nitric oxide (FeNO) in asthma management. Comparative Effectiveness Reviews, 197. 2017. 4. Petsky HL et al. Tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils): a systematic review and meta-analysis. Thorax. 2018;73(12):1110-1119. 5. Dweik RA et al. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FeNO) for clinical applications. Am J Respir Crit Care Med. 2011;184(5):602-15. 6. Menzies-Gow A et al. Clinical utility of fractional exhaled nitric oxide in severe asthma management. Eur Respir J. 2020;55(3):1901633. 7. NIOX®. Data on File; MKT-DOF-006. March 2023.
* Hypothetical patients