NIOX® vs other devices

Discover the differences between NIOX® and other devices

Why choose NIOX®?

Fully conforms to the ATS & ERS Standards¹

With no unexpected servicing, reconditioning, and direct NO measurement, NIOX® is designed with healthcare professionals in mind, whether that is primary care or secondary care.

NIOX® is the only FeNO technology available in the EU and US markets that follows the published ATS & ERS online measurement protocols in full, including inhalation of NO-free air.^1,2

The key differences

Truly removes
ambient NO

Fully conforming the the ATS & ERS standards, the integrated NIOX NeutroNO™ scrubber truly removes ambient nitric oxide on inhalation, alongside only taking in the last few seconds of the exhalation flow to analyse the lower airways.^1-4

No servicing, recalibration or downtime

NIOX®’s pre-calibrated sensors eliminate downtime, have no servicing, recalibration or waiting, and are always ready.

Self-contained and fully dependable

As a standalone desktop device, NIOX® can be used plugged in or on its all-day battery life, making it ready for testing on the go.

Compare NIOX®

Only compared with FeNO devices that are both FDA / CE approved.

	NIOX®	Other devices
Fully conforms to ATS & ERS Standards Complete peace of mind with technical standards.	Yes¹	No
Removes ambient NO on inhalation To ensure results are accurate and just from the patient.	Yes^3,4	Not common
Service free design, meaning no clinical downtime No additional cost for servicing or from downtime.	Yes	Not common
≥99.99% bacterial and ≥99.97% viral filtration efficiency Protecting both you and your patients.	Yes⁵	Not common
Constant audio and visual aids Accessible for all patients with clear and constant audio and visuals aids.	Yes	Not common
No reliance on battery life for testing Never have to wait to charge the device, start testing immediately.	Yes	No
Research paper features NIOX® is considered the technology of choice.¹	~5,440¹	<1000¹

NIOX® Pricing

Competitively priced

With no hidden costs, NIOX® is priced competitively.
Contacting a NIOX® distributor directly is the best way to access the best pricing and to ensure you receive the right package for your clinic’s needs.

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NIOX® is cost effective⁶

NIOX PRO® is 20% more affordable than NIOX VERO®, helping you reduce costs without compromising on performance.⁵ Combine this with our trade-in offer, and switching to NIOX® becomes an easy decision.

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NIOX® vs Other Devices FAQs

Ambient nitric oxide (NO) levels can vary dramatically from as low as 2 ppb to over 500 ppb depending on the environment.⁷ If ambient NO is inhaled during testing, it can contaminate the exhaled breath sample and artificially elevate the FeNO result.^8-10 This may lead to inaccurate assessments of airway inflammation, potentially resulting in misdiagnosis or inappropriate treatment decisions.

By removing ambient NO, on inhalation and before the measurement begins, clinicians can be confident that the measured FeNO reflects the patient’s own NO production, providing a more accurate and reliable indicator of airway inflammation.^3,4,11

To fully conform to the ATS / ERS standards, a controlled ambient environment (ambient NO < 5 ppb) is essential to ensure the breath sample starts from a known baseline with no interference.² While it may be difficult to control environmental nitric oxide concentrations, NIOX® devices remove ambient NO from the inhaled air before testing.^3,4

Before the FeNO measurement, the user inhales through the patented NIOX® Breathing Handle containing a NeutroNO® scrubber. The scrubber removes ambient nitric oxide (NO) from the inhaled air, preventing it from contaminating the exhaled breath sample.

This initial 4-5 second inhalation is a quick, easy, but essential step that removes the influence of ambient NO before the measurement begins. Environmental NO levels can range from 2 ppb to 500 ppb, and without a clean inhalation, ambient NO could artificially elevate the FeNO reading.^8-10 By eliminating this source of contamination, the measured FeNO value accurately reflects the patient's own airway NO production.

Removing ambient NO helps ensure accurate, reliable, and reproducible FeNO measurements that clinicians can trust, supporting confident clinical decision-making.^8,12

NIOX® is widely regarded as the technology of choice for FeNO testing, with decades of clinical use and extensive validation in airway inflammation assessment.¹ NIOX® technology is trusted by healthcare professionals worldwide and is supported by a large body of clinical evidence, helping clinicians make informed decisions in the diagnosis and management of asthma.¹

Its proven accuracy, reliability, ease of use, and seamless integration into clinical workflows have made NIOX® the benchmark against which other FeNO technologies are often compared.^11-13

NIOX® pioneered standalone FeNO testing with the introduction of the first commercially available FeNO device in 1998. This innovation helped bring airway inflammation measurement into routine clinical practice, enabling healthcare professionals to assess eosinophilic inflammation quickly and non-invasively at the point-of-care.

With more than two decades of experience and continuous innovation, NIOX® remains a leader in FeNO testing and has helped establish FeNO as an important tool in the diagnosis and management of asthma.

Battery-dependent devices can create delays and frustration when testing is needed but the device requires charging. With NIOX®, testing can begin immediately when the device is plugged in, regardless of battery status. This helps avoid interruptions to clinic workflow, reduces the risk of missed or delayed appointments, and ensures the device is always ready when patients are. For busy clinics, eliminating charging-related downtime can improve efficiency and reduce user frustration.

The NIOX® difference

What makes NIOX® different?

Fully conformant to ATS&ERS standards¹

NIOX® is the only portable device to fully conform to the ATS & ERS standards for FeNO testing.¹ Which is one of the reasons, it is the technology of choice!¹

The ultimate NIOX® testing experience

NIOX PRO® is designed by NIOX® but inspired by you. This is the best FeNO testing experience that NIOX® has ever engineered, and you can only get that with NIOX®.

The gold standard technology¹

Featuring in the most clinical studies, and used by thousands of healthcare professionals around the world: NIOX® technology is considered the gold standard.^1,14,15

Measures Nitric Oxide

Some FeNO devices estimate FeNO using gas conversions and complicated algorithms. With NIOX®, we simply measure NO directly.

No reconditioning or servicing

NIOX® devices are pre-calibrated, so no waiting between tests, and no servicing or maintenance is required. Never worry about downtime with NIOX®.