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Replication of the natural behaviour required to perform a FeNO measurement using NIOX VERO Replication of the natural behaviour required to perform a FeNO measurement using NIOX VERO

Accurately assess and monitor airway inflammation

While airway inflammation is known to be the major underlying characteristic of asthma, there are few methods of measuring it. Evaluating airway inflammation using induced sputum or airway biopsy is considered the gold standard however it is expensive, invasive, time-consuming, and often not readily available.

The majority of patients with asthma have Type 2/Th2 allergic/eosinophilic driven airway inflammation and higher levels of nitric oxide (NO) in their exhaled breath.4 By measuring the concentration of NO in an exhaled breath (fractional exhaled nitric oxide or FeNO), clinicians can evaluate airway inflammation in patients with asthma.

NIOX VERO® is a non-invasive, simple and safe, and time-saving FeNO device which offers:

  • Accurate FeNO results in a single measurement at the point‑of‑care5
  • FeNO results in approximately ONE minute
  • Routine FeNO monitoring to aid in treatment optimization
  • The ability to evaluate an asthma patient’s response to anti-inflammatory therapy

To date, over 18 million tests have been performed using a NIOX device, supporting clinicians to enhance the accuracy of diagnosis and better-personalized control.1

References: 1. Data on file. Circassia Ltd March 2018. 2. Alving K, Malinovschi A. Basic aspects of exhaled nitric oxide. Eur Respir Mon. 2010;49:1-31. 3. Peirsman EJ, Carvelli TJ, Hage PY, et al. Exhaled nitric oxide in childhood allergic asthma management: a randomized controlled trial. Pediatr Pulmonol. 2014;49(7):624-631. 4. Dweik RA, Boggs PB, Erzurum SC, et al; on behalf of the American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications. An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications. Am J Respir Crit Care Med. 2011;184(5):602-615. 5. Maniscalco M et al. Fractional exhaled nitric oxide-measuring devices: technology update. Medical Devices Evidence and Research. June 2017.