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NIOX® Heritage

Over 29 years of FeNO testing innovation

At NIOX® we are proud to be the pioneers behind commercial FeNO testing!

Discover the FeNO by NIOX® story:

1989

Discovery of NO in biology

The importance of nitric oxide was established in the late 1980s when scientists discovered this tiny molecule had signalling properties. Their work would eventually lead to a Nobel Prize.

1991

Discovery that NO is present in exhaled breath

Researchers at the Karolinska Institute in Sweden identified the presence of NO in human lungs.

1992

NO is molecule of the year

Science magazine names NO its Molecule of the Year, citing the versatility and importance of the gas.

1993

Discovery that NO is increased in asthma patients

Scientists demonstrate that asthma patients exhale increased levels of NO.

1994

Discovery that NO is decreased after steriod therapy in asthma

A reduction in NO after steroid therapy in asthma patients is uncovered for the first time.

1998

Nobel prize for the discovery of NO as a signalling molecule

The Nobel Prize in Physiology or Medicine was awarded for discoveries concerning NO as a signalling molecule.

NO Discoveries:

1988-1998

1998

Creation of 'NIOX®'

The scientists that discovered FeNO and it's link to asthma start a company called Aerocrine AB in 1997 and launched the first FeNO device for commercial use in 1998.

2000

The next generation: NIOX® Flex

NIOX FLEX® receives approval as a medical device in Europe, enhancing testing capabilities for healthcare professionals in the diagnosis and management of asthma.

2005

NIOX MINO®: The world's first portable FeNO device

The introduction of NIOX MINO® offers users a hand-held, portable FeNO analyser for the first time.

2005

Introduction of ERS and ATS joint standards of FeNO testing

The European Respiratory Society (ERS) and the American Thoracic Society (ATS) publish a joint recommendation on the standardisation of FeNO and nasal NO (nNO) measurement techniques.

NIOX® Founded:

1998-2008

2011

ATS Guidleines on Interpreting FeNO

The ATS guidelines are released with individual cut-off points for asthma diagnosis and management with FeNO.

2013

NIOX VERO® Launched

NIOX® releases the new NIOX VERO®, designed on user feedback, NIOX VERO® becomes the flagship FeNO testing device.

2017

NIOX® Nasal introduced for nNO testing

NIOX VERO® introduces the nasal application for the measurement of nNO, bringing new options for the diagnosis of primary ciliary dyskinesia (PCD).

2018

FeNO testing recognised in GINA

For the first time, GINA recognises the importance of FeNO testing to help assess the Type 2 phenotype and select the right biologic in severe asthma patients.

2019

ARTP Award Winner

NIOX® wins Small Diagnostic Manufacturer of the Year 2019 from the Association for Respiratory Technology and Physiology (ARTP).

2020

Medtech Award: Winner

NIOX VERO® wins MedTech Award for the Most Advanced Asthma Solution 2020

2021

40 million FeNO tests with NIOX®

Over 40 million FeNO tests have been performed with NIOX® technology, a major milestone.

2021

Healthcare and Pharmaceutical Awards: Winner

NIOX® takes home Global Leaders in FeNO Testing 2021 at the Global Health and Pharma Awards.

2021

technology Awards: Winner

NIOX VERO® is named Most Innovative Asthma Management Technology 2021 at the Global Health and Pharma Awards.

2022

M&A Today - Global Awards: Winner

NIOX® is awarded Best FeNO Testing Provider at the M&A Today Global Awards 2022.

2022

AI Research and Development Award: Winner

NIOX® wins Leaders in FeNO Testing Technology Development at the AI Research & Development Awards 2022.

2023

50 million FeNO tests with NIOX®

At NIOX® we are dedicated to transforming asthma care. That’s why we are excited to announce 50 million FeNO tests have now been performed with NIOX® technology!

FeNO by NIOX®:

2008-2023

Celebrating

25 Years of NIOX®

In 2023 we are proud to celebrate 25 years of NIOX® technology. From a chance discovery to millions of tests peformed, learn more about the full NIOX® story here.

25 Years of NIOX®:

2023

2024

55 Million FeNO tests performed with NIOX®

Another key milestone reached! We are delighted to share that 55 million FeNO tests have been performed with NIOX® Technology.

The future of FeNO:

Today

Ready for NIOX®?

Request a quote for a device today with our simple and easy to use quotation tool. Used by thousands of healthcare professionals, NIOX® is the global device of choice for FeNO testing.

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More about NIOX®:

The device of choice: NIOX VERO®

Learn more about the gold standard FeNO testing device.

NIOX VERO®

The company that cares about FeNO

Discover why you should choose NIOX® as your FeNO partner.

Why NIOX®

The technology of choice

Learn more about the amazing technology powering NIOX®.

NIOX® Technology

Discover FeNO Testing

Learn about FeNO with our free app

Why NIOX®

Explore the Gold Standard device

Understand FeNO Scores

Use our interpreting FeNO calculator

NIOX® Customer Support and Training

At NIOX® we are passionate about providing excellent support and training.

© Copyright NIOX Group plc. MKT-PRM-WW-0089. May 2024.